The results of the PrEPVacc HIV vaccine trial conducted in Eastern and Southern Africa, which ran between 2020 and 2024, show conclusively that neither of the two experimental vaccine regimens tested reduced HIV infections among the study population. Vaccinations in the PrEPVacc trial were stopped in November 2023 (and publicly announced in December 2023) when it became clear to independent experts monitoring the study data that there was little or no chance of the vaccines demonstrating efficacy in preventing HIV acquisition. The PrEPVacc vaccine trial results, announced today at AIDS…
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