By Staff Reporter
Preliminary data from the U.S. Centers for Disease Control and Prevention indicates that seasonal influenza continues to cause significant illness across the United States. So far this season, the CDC estimates at least fifteen million flu cases, one hundred eighty thousand hospitalizations, and seven thousand four hundred deaths. Health officials stress that these figures may change as additional reports are received.
Seasonal influenza activity remains high nationwide. While some indicators show a slight decrease or have remained stable compared to last week, experts caution that this may reflect changes in healthcare seeking or reporting during the holiday period rather than a true decline in flu activity. The country is expected to experience elevated influenza levels for several more weeks, and the CDC has classified the 2025-2026 season as moderately severe.
Of particular concern are pediatric cases. This week, eight influenza-related deaths among children were reported, bringing the total for the season to seventeen. Public health authorities continue to urge parents to protect their children through vaccination and early treatment when symptoms appear.
Influenza A(H3N2) has been the most commonly detected virus this season. During Week 53, public health laboratories reported one thousand two hundred fifty-nine influenza viruses, of which one thousand two hundred twenty-three were influenza A and thirty-six were influenza B. Among the subtyped influenza A viruses, seven point seven percent were A(H1N1)pdm09 while ninety-two point three percent were A(H3N2). Further genetic testing of A(H3N2) samples collected since late September showed that over ninety-one percent belonged to subclade K, highlighting the continued evolution of the virus.
Testing by clinical laboratories across the country shows that out of one hundred two thousand five hundred eighteen specimens in Week 53, twenty-five thousand three hundred forty-three were positive for influenza, representing nearly twenty-five percent of samples. Influenza A accounted for ninety-four percent of positive results while influenza B made up six percent. These numbers underline the dominance of influenza A viruses in the current season.
Regional differences are evident. Region 8 reported the highest proportion of positive respiratory specimens at thirty-one point seven percent while Region 10 had the lowest at thirteen percent. The distribution of circulating viruses varies by area, emphasizing the need for localized monitoring and response efforts.
Vaccination remains the most effective tool for reducing flu risk and preventing serious complications. This season, approximately one hundred thirty million doses of influenza vaccine have been distributed across the United States. Health authorities encourage people to get vaccinated even at this stage to reduce their risk of illness. In addition to vaccines, prescription antiviral drugs can treat influenza. Early initiation of these medications is particularly important for individuals at high risk of severe disease, including older adults, young children, and those with underlying health conditions.
Influenza viruses are not the only pathogens affecting respiratory health this season. COVID-19 and respiratory syncytial virus continue to circulate alongside flu, and the CDC provides integrated updates on all three illnesses to help clinicians and the public respond appropriately.
There were no new reports of avian influenza A(H5) infections in humans this week. To date, person-to-person transmission of H5 viruses has not been observed in the United States, reducing the immediate risk from this virus strain.
Public health authorities emphasize that even during periods of holiday travel and gatherings, vigilance is essential. Hand hygiene, respiratory etiquette, and vaccination remain key strategies for reducing the spread of influenza. With several more weeks of elevated activity expected, officials urge Americans to take flu seriously, monitor symptoms, and seek care promptly when necessary.
